Set the Instant Pot to saute. Add ground beef, breaking up with a wooden spoon as you cook until the ground beef is browned throughout, about 5 minutes. Turn off the Instant Pot and drain away any excess drippings.
Add Stone House Seasoning, dried oregano, crushed tomatoes, and water. Stir to combine. Place the spaghetti noodles on top of the meat mixture. Add additional water as needed to make sure that all of the spaghetti noodles are covered.
Secure the lid onto the Instant Pot and cook for 8 minutes at high pressure. Once cooking has completed, carefully use the quick release to release the remaining pressure. Remove the lid of the Instant Pot and stir the spaghetti to combine.